Advancing the state of medical knowledge and clinical practice has been part of Alpha Healthcare’s DNA since the company opened its first medical lab in 1971. Despite the accelerating pace of new developments in disease prevention, diagnosis and treatment – and the pressure on practitioners to do more with less due to the aging population and constrained funding – Alpha remains firmly committed to its mission of Advancing Healthcare for All.

Recognizing that the burgeoning field of information technology offered new possibilities for improving the quality of patient care and enhancing healthcare outcomes, in 2000 Alpha created Alpha IT – a division of the company focused on conducting information technology research and developing innovative software solutions to contemporary healthcare challenges.


Our Approach


  Leveraging the diverse insights of its multidisciplinary R&D team.

To achieve its mission, Alpha has assembled an unrivalled team of 35 in-house researchers, many of whom hold Doctorate or Masters degrees in such diverse fields as computer science, business administration, engineering, chemistry and clinical research. These research personnel are actively engaged in both basic research and applied research.

  Following a disciplined methodology that begins with basic research.

Every basic research project Alpha undertakes arises from the observation of an unmet need or opportunity to enhance the practice of healthcare.
After rigorously defining the problem and proposing conceptual solutions, we review the literature and assemble the mathematical and computer science tools needed to solve the problem.
In an iterative manner, we evaluate each conceptual solution and collect relevant data, conduct simulations and then revise our solution until we arrive at a working, validated prototype.

  Conducting all research activity in Canada, not overseas.

Alpha has always been deeply committed to expanding the capabilities of healthcare researchers here in Canada. Rather than reaping potential cost-savings from contracting overseas personnel to conduct our research activities, we hire the best and brightest new talent here at home, then offer these individuals the opportunity to expand their knowledge and skills by working alongside the most experienced minds in healthcare research.


Our Research

The following research studies have been presented at international conferences and published in conference proceedings:


Download (PDF)

Antimicrobial Resistance of Urinary Gram-Negative Bacilli Recovered from Pregnant Patients

Conference: American Society for Microbiology General Meeting, Boston, MA, USA, May 2014

Download (PDF)

Tracking Methicillin-Resistant Staphylococcus aureus among Community Clinical Isolates: A Five-Year Study

Conference: American Society for Microbiology General Meeting, Denver, CO, USA, May 2013

Download (PDF)

Increasing Rates of Extended-Spectrum Beta-Lactamase (ESBL) Producing Strains among Community Urinary Isolates and Impact of Patient Age on ESBL Prevalence and Resistance Rates: A Five-Year Study

Conference: American Society for Microbiology General Meeting, San Francisco, CA, USA, June 2012

Download (PDF)

Prevalence of Multidrug-Resistant Gram-Negative Bacilli (MDR-GNBs) among Community Urinary Isolates, and Impact of Patient Age on MDR-GNB Prevalence and Resistance Rates

Conference: American Society for Microbiology General Meeting, New Orleans, LA, USA, May 2011

The following research studies have been presented at international conferences and published in conference proceedings:


Download (PDF)

Evaluation of Predictive Learners for Cancer Incidence and Mortality

By: Smita Kachroo, William W. Melek University of Waterloo, Alpha Global IT Toronto, Canada

Download (PDF)

Integrating Semantic Medical Entity Relations for Disease Prediction Using SNOMED-CT Terminology

By: Mariam Daoud, Jimmy Xiangji Huang, William Melek and Joseph Kurian

Download (PDF)

A Time Series Based Method for Analyzing and Predicting Personalized Medical Data

By: Qinwin Vivian Hu, Xiangji Jimmy Huang, William Melek, and C. Joseph Kurian.
Information Retrieval and Knowledge Management Research Lab York University; Alpha Global IT, Toronto, Canada

Download (PDF)

A Semantic Feature Space for Disease Prediction

By: Mariam Daoud, Jimmy Xiangji Huang, William Melek, C. Joseph Kurian
Information Retrieval and Knowledge Management Research Lab School of Information Technology, York University,Toronto, Canada


Our Partnerships



While Alpha possesses a wealth of internal expertise, it actively engages in strategic partnerships with leading academic institutions to explore new frontiers in health science. Presently, Alpha has research agreements in place with three leading universities, namely the University of Waterloo, York University and the University of Guelph. In each case, a mix of undergraduate and graduate students, post-doctoral students and professors spend significant time each week working on projects at Alpha Healthcare. Earlier academic partners included the University of Toronto and Ryerson University.





Patents and Projects


Over the past decade, Alpha Healthcare has been actively working on a range of projects – many involving Artificial Intelligence (AI) and Artificial Neural Networks (ANN) – to help advance the quality of care provided by physicians, and improve the efficacy and efficiency of the broader healthcare system.

The company’s research strength is borne out by the fact that it holds two patents and two certified industrial designs (in Canada and internationally); have another five projects at the patent application stage; and are actively exploring several other leading-edge fields of inquiry that will significantly enhance disease treatment protocols and everyday clinical practice.